SS
was attacked by smallpox in 1688, but survived. As she grew older her sight deteriorated until she could not read a word without glasses (which made her consider that she ought to spend more time in prayer and meditation instead of reading).
Matthew, Henry Colin Gray et al., editors. Oxford Dictionary of National Biography. http://www.oxforddnb.com/.
Williams, Sir John Bickerton, and Sarah Savage. Memoirs of the Life and Character of Mrs. Sarah Savage. Holdsworth and Ball.
CS
's face was permanently scarred by her father's amateur smallpox inoculation. Her great-niece Lucy Walford, however, felt very strongly that this fact pushed her to develop her talents and personality, making her a universal favourite.
Walford, Lucy. Recollections of a Scottish Novelist. Williams and Norgate.